Our Technology

About The Transformative
RaniPill® Capsule

Rani Therapeutics has developed a disruptive technology to enable orally administered biologics and drugs. The RaniPill® is a simple-to-swallow robotic capsule that delivers biologics orally, offering injectable-like bioavailability without a needle.

Rani's technology enables oral delivery of hundreds of approved biologic drugs that currently lack oral formulations, providing an opportunity to expand markets in immunology, endocrinology, oncology, and other key therapeutic areas.

Platform Advantages

Why the RaniPill® is different

High Bioavailability
Delivered through the highly vascularized intestinal wall, achieving bioavailability comparable to or better than subcutaneous injections.
Minimal Discomfort
The self-inflating balloon has been designed to minimize GI discomfort. The injection is painless and the drug is rapidly absorbed.
Scalable Design
Vertically integrated manufacturing strategy allows for rapid product iteration and the ability to rapidly scale manufacturing capacity.
Agnostic to Payload
Can accommodate therapeutic peptides, proteins, antibodies and nucleotides across a wide range of therapeutic areas.
Clinical Data
The RaniPill® capsule demonstrates encouraging results in humans with proven safety and tolerability across multiple trials.
Strong Patent Position
400+ granted and pending patent applications covering both the platform and drugs in combination with the platform.
How It Works

See the RaniPill® in action

Watch how the capsule travels from swallow to systemic absorption — engineered for protection and precise delivery of biologics.

Proven Results

Clinical data that speak volumes

The RaniPill® platform has demonstrated clinical proof of concept across 19 different biologic molecules, including peptides, proteins, and monoclonal antibodies, in 146 patients with 233 administrations, achieving bioavailability comparable to subcutaneous injections with no serious adverse events. 100% of patients in clinical trials have successfully swallowed RaniPill®.

Explore our pipeline →
3
Phase 1 studies completed
233
RaniPills administered to 146 humans
20
Preclinical molecules assessed: antibodies, peptides, and large proteins with high bioavailability
60-GLP
Study and repeat dose clinical study completed with no findings

Interested in our platform?

The Rani platform is capable of orally delivering any payload, including proteins, peptides, and antibodies.